Test Bank for Robbins Basic Pathology 10th Edition Kymar Abbas
Chapter 7. Genetic and Pediatric Diseases
1 Genetic disorders that involve a single gene trait are
A) multifactorial gene mutations.
B) chromosome rearrangements.
C) Mendelian patterns of transmission.
D) abnormal numbers of chromosomes.
2 In addition to having a 50% chance of inheriting an
autosomal dominant disorder from an affected parent, such a
disorder is characterized by:
A) aneuploidy of genes in all cells.
B) deficiencies in enzyme synthesis.
C) affected X transmission to daughters.
D) varied gene penetration and expression.
3 Autosomal recessive disorders are characterized by:
A) age of onset later in life.
B) abnormal protein structure.
C) inborn errors of metabolism.
D) one in two risk of a carrier child.
4 When a male child inherits an X-linked disorder from his
heterozygous carrier mother,
A) his sons will be carriers.
B) his father has the disorder.
C) some of his sisters will be carriers.
D) his daughters will have the disorder.
5 Multifactorial inheritance disorders, such as cleft palate, are
often caused by during fetal development.
A) multiple gene mutations
B) dominant gene expression
C) X-linked crossover problem
D) polyploidy of chromosomes
6 The newborn has the distinctive physical features of trisomy
21, Down syndrome, which includes:
A) upward slanting of eyes.
B) large, protruding ears.
C) thin lips and small tongue.
D) long fingers with extra creases.
7 Aneuploidy of the X chromosome can result in a monosomy
or polysomy disorder. The manifestations of monosomy X,
Turner syndrome, differ from polysomy X disorders in
numerous ways that include:
A) short-stature female individual..
B) mental retardation.
C) enlarged breasts.
D) early onset puberty.
8 A teratogenic environmental agent can cause birth defects
A) inherited as a recessive trait.
B) intense exposure occurs at birth.
C) disjunction occurs during meiosis.
D) retained during early pregnancy.
9 Fetal alcohol syndrome (FAS) is unlike other teratogens in
that the harmful effects on the fetus:
A) directly result in liver damage.
B) extend throughout the pregnancy.
C) is most noticeable in adulthood.
D) cause death in early childhood.
10 Prenatal diagnosis methods include the use of
ultrasonography for identifying abnormalities.